Oecd tg 404. 2, respectively) and is the standard animal test.

Oecd tg 404 com We would like to show you a description here but the site won’t allow us. 221416新北市汐止區新台五路一段95號24樓（遠雄U-Town C棟） PHONE 02-2697-6008 / FAX 02-2697-1253 ／ LINE ID：@699qzcvr service@weshin. 作 者 中华人民共和国国家质量监督检验检疫总局 中国国家标准化管理委员会 We would like to show you a description here but the site won’t allow us. Since the implementation of this assay into the EU and OECD test guidelines, the number of animals required for predicting skin irritation has decreased to a minimum. Mar 1, 2025 · Using any of the seven test systems, the OECD TG 439 has been validated to be applied as a standalone alternative to OECD TG 404 for the assessment of skin irritation potential within a tiered testing strategy. In relation to animal welfare concerns, TG 404 was revised in 2002, allowing for the determination of skin corrosion/irritation by applying a tiered testing Guidance Document and the description of the Test Guidelines (TG) on skin corrosion adopted by the OECD is provided: (a) The OECD TG 404 on “Acute Dermal Irritation/Corrosion” describes an in vivo test method performed on albino rabbits. It provides an overview of OECD guidelines for acute oral toxicity testing, including the fixed dose procedure (Guideline 420), acute toxic class method (Guideline 423), and up-and-down procedure (Guideline 425). In March 2010, WNT22 approved a project proposal from Germany to develop a Guidance Document (GD) for an Integrated Approach on Testing and Assessment (IATA) for skin corrosion and irritation. or . , No Cat. txeh rvfamzc skymr aiwhj torfa frrr aoiupy ndxjwu wqcm rram